The NDUFS7 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to CI-20KD, and NDUFS7. This antibody recognizes Human, Mouse, and Rat antigen. The NDUFS7 Polyclonal Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain. This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic lesions in subcortical brain regions